Total Pages: 118

Topics Covered:

Pharmacology Section

• Scientists’ Contributions

• Basic Definitions (Pharmacology, Pharmacodynamics, Pharmacokinetics, Toxicology, etc.)

• Pharmacokinetics (Absorption, Distribution, Metabolism, Excretion)

• Pharmacodynamics & Mechanism of Drug Action

• Drug Interactions, Tolerance & Resistance

• Adverse Drug Reactions (Type A & B, Teratogenicity, Carcinogenicity, etc.)

• Cholinergic System & Drugs (Agonists, Anticholinesterases, Anticholinergics)

• Adrenergic System & Drugs (Sympathomimetics, Antiadrenergics, β-blockers)

• Histamine & Antihistaminics

• 5-HT (Serotonin) & Antagonists

• Drug Therapy of Migraine

• Prostaglandins, Leukotrienes, Platelet Activating Factor

• NSAIDs & Antipyretic-Analgesics

• Antirheumatoid Drugs & DMARDs

• Drugs Used in Gout

• Drugs for Cough & Bronchial Asthma

• Pituitary Hormones (GH, ACTH, Prolactin)

• Thyroid Hormones & Inhibitors

• Insulin & Oral Hypoglycemics

• Corticosteroids

• Androgens & Drugs for Erectile Dysfunction

• Estrogens, Progestins & Contraceptives

• Oxytocin & Uterine Drugs

• Drugs Affecting Calcium Balance (Calcitonin, Vitamin D, Bisphosphonates)

• Skeletal Muscle Relaxants

Medicinal Chemistry Highlights (Integrated SAR Points)

• Structural features of Aspirin & other NSAIDs (COX selectivity, prodrug forms like Sulindac)

• Chemistry & selectivity of β-blockers (1st, 2nd, 3rd generation)

• Salicylates, Propionic acid derivatives, Oxicam & Pyrazolone chemistry notes

• Diuretic features (–SO₂NH₂ group importance, chondroprotective action of Aceclofenac)

• Steroidal vs Non-steroidal estrogen/progestin compounds

• Corticosteroid nucleus & modifications affecting activity

• Insulin analogues & recombinant DNA preparation insights

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